Medical Microbiology and Infection at a Glance. Stephen H. GillespieЧитать онлайн книгу.
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Table of Contents
1 Cover
5 Preface to the fifth edition
7
Part 1: Concepts
1 Microbial pathogens, classification and concepts
Characteristics of bacteria
Bacterial structural components
Bacterial classification
Medically important groups of bacteria
2 Innate and acquired immunity
Phagocytes
Complement and other plasma proteins
The adaptive (specific) immune response
Damaging immunity
3 The ‘normal’ flora in health and disease
Normal flora
Physical and chemical barriers
4 Pathogenicity and pathogenesis of infectious disease
Definitions
Types of pathogen
Mechanisms of pathogenicity
Damaging the host
5 Making a microbiological diagnosis of infection
Specimens
Laboratory examination
Culture
Identification
Susceptibility testing
Serology
Molecular techniques
6 Antimicrobial therapy – principals and concepts
Adverse events
Acute allergy and intolerance
Targeting treatment
Monitoring therapy
7 Antibacterial agents – pharmacology and modes of action
Beta‐lactam antibiotics
Penicillins
Cephalosporins
Monobactams
Carbapenems
Aminoglycosides
Glycopeptides
Daptomycin
Quinolones
Macrolides
Streptogramins
Oxazolidinones
Metronidazole
Tetracyclines
Sulphonamides and trimethoprim
8 Antimicrobial use and stewardship
A holistic approach in antibiotic therapy
Antibiotic prescribing policies
Choice of therapy
Routes of administration
Choosing an antibiotic
9 Emergence and detection of resistance
Transmission of resistance determinants between bacteria
Mechanisms of resistance
10 Sources and transmission of infection
Sources of infection
Survival and transmission
11 Principles of infection control
Identifying an outbreak
Infection control
Isolation
12 Infection in the healthcare environment
The environment
The host
Medical activities
13 Immunization
Immunization
Vaccine