Applied Organic Chemistry. Surya K. DeЧитать онлайн книгу.
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Applied Organic Chemistry
Reaction Mechanisms and Experimental Procedures in Medicinal Chemistry
Surya K. De
Volume 1
Copyright
Author
Dr. Surya K. De
Supra Sciences
San Diego, CA
United States
Cover Image:
© enot‐poloskun/Getty
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Print ISBN: 978‐3‐527‐34785‐8
ePDF ISBN: 978‐3‐527‐82815‐9
ePub ISBN: 978‐3‐527‐82817‐3
oBook ISBN: 978‐3‐527‐82816‐6
Preface
Organic chemistry is a constantly developing and expanding field of science because of its infinite research and application possibilities. Clear understanding of organic chemistry concepts, including the mechanistic aspects of organic reactions, helps chemists design drug molecules with the power to save human lives.
This textbook is targeted to advanced undergraduates and postgraduate students in all areas of organic, bioorganic, pharmaceutical, and medicinal chemistry. Professional researchers may utilize it as a handbook due to its references to original literature, recent reviews, and application of named reactions and reagents frequently used in organic synthesis. This book also covers, step by step, the mechanism of selected reactions that are part of undergraduate and postgraduate curricula. The definition of each named reaction with its original reference(s), i.e. the first one or others if applicable, current reviews, and their applications (sourced from Journal of Medicinal Chemistry and others) are also included. Heterocyclic compounds have important biological activities, so the nomenclature and application of heterocyclic compounds have been summarized in Chapter 9. In addition, Chapter 12 presents preliminary concepts regarding solution‐phase and solid‐phase peptide syntheses. For synthetic stand points, common organic reagents and functional groups transformation are discussed in Chapters 13–16.
References included in this book are available on PubMed (https://www.ncbi.nlm.nih.gov/pubmed) or https://pubs.acs.org. The experimental procedure of each reaction can be found on Google Patents (http://patents.google.com).
I would like to express great thanks to Dr. Ramkrishna De (Vertex Pharmaceuticals) for reviewing the manuscript and providing valuable suggestions. Also, Dr. Maloy Kumar Parai provided some assistance in preparing the manuscript.
I would like to express great